Assay Detail
Functional
CHEMBL654475
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activity for Beta-1 adrenergic receptor was assessed from ability to stimulate contractions in isolated guinea pig atrium.
2
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Cardiac atrium |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Alpha- and beta-adrenoceptors: from the gene to the clinic. 2. Structure-activity relationships and therapeutic applications.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.16 | 8.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1160723 | LEVISOPRENALINE | 2.0 | 2 | 8.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1160723 | LEVISOPRENALINE | EC50 | = | 2.2 | nM | 8.66 |
| CHEMBL1160723 | LEVISOPRENALINE | EC50 | = | 2200.0 | nM | 5.66 |