Assay Detail
Functional
CHEMBL654479
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Beta-1 adrenergic receptor agonist activity by stimulation of contraction rate of isolated guinea pig atrial preparations
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Cardiac atrium |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Syntheses and adrenergic activities of ring-fluorinated epinephrines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.48 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL287587 | — | — | 1 | 6.52 |
| CHEMBL281232 | — | — | 1 | 4.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL287587 | — | EC50 | = | 300.0 | nM | 6.52 |
| CHEMBL281232 | — | EC50 | = | 36000.0 | nM | 4.44 |