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Assay Detail

CHEMBL654946

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
The compound was tested in vitro for its ability to block Beta-1 adrenergic receptor n guinea pig trachea
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cavia porcellus
Tissue Trachea
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Beta-1 adrenergic receptor (CHEMBL5471)
Type SINGLE PROTEIN
Organism Cavia porcellus

Publication

Ultra-short-acting beta-adrenergic receptor blocking agents. 1. (Aryloxy)propanolamines containing esters in the nitrogen substituent.
Erhardt PW, Woo CM, Gorczynski RJ, Anderson WG.
J Med Chem (1982) 25 : 1402 -1407
PubMed 6130153 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 5.90 5.90

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL31591 1 5.90

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL31591 Kd = 1258.93 nM 5.90