Assay Detail
Binding
CHEMBL660140
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against bovine cathepsin D
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Renin inhibitors. Design and synthesis of a new class of conformationally restricted analogues of angiotensinogen.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 7.34 | 7.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL98582 | — | — | 1 | 7.34 |
| CHEMBL101874 | — | — | 1 | - |
| CHEMBL445118 | — | — | 1 | - |
| CHEMBL318242 | — | — | 1 | - |
| CHEMBL97865 | — | — | 1 | - |
| CHEMBL321937 | — | — | 1 | - |
| CHEMBL433013 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL98582 | — | IC50 | = | 46.0 | nM | 7.34 |
| CHEMBL101874 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL445118 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL318242 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL97865 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL321937 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL433013 | — | IC50 | > | 10000.0 | nM | - |