Assay Detail
Binding
CHEMBL661860
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Binding affinity against rat Cathepsin G
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis of peptidyl fluoromethyl ketones and peptidyl alpha-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin G.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.40 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL130006 | — | — | 1 | 6.70 |
| CHEMBL130190 | — | — | 1 | 6.70 |
| CHEMBL132171 | — | — | 1 | 5.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL130006 | — | Ki | = | 200.0 | nM | 6.70 |
| CHEMBL130190 | — | Ki | = | 200.0 | nM | 6.70 |
| CHEMBL132171 | — | Ki | = | 1600.0 | nM | 5.80 |