Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL663196

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig trachea using [3H]LTD4
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cavia porcellus
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Cysteinyl leukotriene receptor 1 (CHEMBL5645)
Type SINGLE PROTEIN
Organism Cavia porcellus

Publication

Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene D4 receptor antagonists. 2. Effects of an additional phenyl ring on receptor affinity.
Huang FC, Galemmo RA, Johnson WH, Poli GB, Morrissette MM, Mencel JJ, Warus JD, Campbell HF, Nuss GW, Carnathan GW.
J Med Chem (1990) 33 : 1194 -1200
PubMed 2157010 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 9.00 9.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL15177 MK-571 1 9.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL15177 MK-571 Kd = 1.0 nM 9.00