Assay Detail
Binding
CHEMBL664975
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Dissociation constant was determined against Cysteinyl leukotriene D4 receptor of guinea pig lung membranes using radioligand binding assays.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Lung |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
(Piperidinylalkoxy)chromones: novel antihistamines with additional antagonistic activity against leukotriene D4.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 5.65 | 5.95 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL267475 | FPL-55712 | — | 1 | 5.95 |
| CHEMBL84407 | — | — | 1 | 5.63 |
| CHEMBL79732 | — | — | 1 | 5.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL267475 | FPL-55712 | Kd | = | 1120.0 | nM | 5.95 |
| CHEMBL84407 | — | Kd | = | 2340.0 | nM | 5.63 |
| CHEMBL79732 | — | Kd | = | 4270.0 | nM | 5.37 |