Assay Detail
Binding
CHEMBL665474
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Ability to displace [3H]DADL from delta opioid receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Delta opioid binding selectivity of 3-ether analogs of naltrindole.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 7.56 | 9.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL567175 | NALTRINDOLE | — | 1 | 9.66 |
| CHEMBL1744389 | — | — | 1 | 8.18 |
| CHEMBL1743886 | — | — | 1 | 7.00 |
| CHEMBL610285 | — | — | 1 | 6.99 |
| CHEMBL1202098 | — | — | 1 | 5.98 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL567175 | NALTRINDOLE | Ki | = | 0.22 | nM | 9.66 |
| CHEMBL1744389 | — | Ki | = | 6.57 | nM | 8.18 |
| CHEMBL1743886 | — | Ki | = | 99.0 | nM | 7.00 |
| CHEMBL610285 | — | Ki | = | 103.0 | nM | 6.99 |
| CHEMBL1202098 | — | Ki | = | 1044.0 | nM | 5.98 |