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Assay Detail

CHEMBL665475

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Binding
Ability to inhibit binding of SNC80 to delta opioid receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Delta-type opioid receptor (CHEMBL269)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Delta opioid binding selectivity of 3-ether analogs of naltrindole.
Coop A, Pinto J, Wang L, McCullough K, Rothman RB, Dersch C, Jacobson AE, Rice KC.
Bioorg Med Chem Lett (1999) 9 : 3435 -3438
PubMed 10617086 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 9.13 10.21

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL567175 NALTRINDOLE 1 10.21
CHEMBL1744389 1 8.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL567175 NALTRINDOLE Ki = 0.062 nM 10.21
CHEMBL1744389 Ki = 9.0 nM 8.05