Assay Detail
Binding
CHEMBL665476
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Binding affinity evaluated by inhibition of binding of [3H]DADLE to delta opioid receptor of rat brain
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
The LMC delta opioid recognition pharmacophore: comparison of SNC80 and oxymorphindole.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 10 | 8.02 | 9.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL609392 | — | — | 1 | 9.15 |
| CHEMBL612090 | — | — | 1 | 8.62 |
| CHEMBL101519 | — | — | 1 | 8.43 |
| CHEMBL612089 | — | — | 1 | 8.34 |
| CHEMBL252172 | BNTX | — | 1 | 8.21 |
| CHEMBL612088 | — | — | 1 | 7.80 |
| CHEMBL609136 | — | — | 1 | 7.77 |
| CHEMBL609135 | — | — | 1 | 7.41 |
| CHEMBL609393 | — | — | 1 | 7.33 |
| CHEMBL609137 | — | — | 1 | 7.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL609392 | — | Ki | = | 0.7 | nM | 9.15 |
| CHEMBL612090 | — | Ki | = | 2.4 | nM | 8.62 |
| CHEMBL101519 | — | Ki | = | 3.7 | nM | 8.43 |
| CHEMBL612089 | — | Ki | = | 4.6 | nM | 8.34 |
| CHEMBL252172 | BNTX | Ki | = | 6.2 | nM | 8.21 |
| CHEMBL612088 | — | Ki | = | 16.0 | nM | 7.80 |
| CHEMBL609136 | — | Ki | = | 17.0 | nM | 7.77 |
| CHEMBL609135 | — | Ki | = | 39.0 | nM | 7.41 |
| CHEMBL609393 | — | Ki | = | 47.0 | nM | 7.33 |
| CHEMBL609137 | — | Ki | = | 75.0 | nM | 7.12 |