Assay Detail
Functional
CHEMBL665630
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration against DU145 prostate cancer cell line
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | DU-145 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis, and evaluation of psorospermin/quinobenzoxazine hybrids as structurally novel antitumor agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.91 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL320647 | — | — | 1 | 7.52 |
| CHEMBL101871 | — | — | 1 | 7.10 |
| CHEMBL369474 | PSOROSPERMIN | — | 1 | 6.68 |
| CHEMBL101299 | — | — | 1 | 6.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL320647 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL101871 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL369474 | PSOROSPERMIN | IC50 | = | 210.0 | nM | 6.68 |
| CHEMBL101299 | — | IC50 | = | 470.0 | nM | 6.33 |