Assay Detail
Binding
CHEMBL665763
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was evaluated for affinity towards Corticotropin releasing factor receptor 2 expressing tissues such as Choroid plexus, blood vessels
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Choroid plexus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Corticotropin-releasing factor receptor 2 (CHEMBL3581) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Potent and long-acting corticotropin releasing factor (CRF) receptor 2 selective peptide competitive antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.96 | 9.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2370918 | ASTRESSIN B | — | 1 | 9.24 |
| CHEMBL440057 | HUMAN CORTICOTROPIN RELEASING FACTOR | — | 1 | 8.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2370918 | ASTRESSIN B | IC50 | = | 0.57 | nM | 9.24 |
| CHEMBL440057 | HUMAN CORTICOTROPIN RELEASING FACTOR | IC50 | = | 2.07 | nM | 8.68 |