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Assay Detail

CHEMBL666279

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
The compound was tested for binding affinity against Cysteinyl leukotriene D4 receptor in guinea pig lung membrane
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cavia porcellus
Tissue Lung
Subcellular Membrane
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Cysteinyl leukotriene receptor 1 (CHEMBL5645)
Type SINGLE PROTEIN
Organism Cavia porcellus

Publication

5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors.
Musser JH, Kreft AF.
J Med Chem (1992) 35 : 2501 -2524
PubMed 1635053 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.22 7.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL162358 TOMELUKAST 2.0 1 7.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL162358 TOMELUKAST Ki = 60.0 nM 7.22