Assay Detail
Binding
CHEMBL666491
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Lung parenchyma |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Evolution of a series of peptidoleukotriene antagonists: synthesis and structure/activity relationships of 1,3,5-substituted indoles and indazoles.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 8.30 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL22776 | POBILUKAST | 2.0 | 1 | 8.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL22776 | POBILUKAST | Ki | = | 5.0 | nM | 8.30 |