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Assay Detail

CHEMBL670409

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Binding
Compound was tested for its effect on dopamine saturation analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

D(2) dopamine receptor (CHEMBL339)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Synthesis and biological evaluation of 1-(1,2-benzisothiazol-3-yl)- and (1,2-benzisoxazol-3-yl)piperazine derivatives as potential antipsychotic agents.
Yevich JP, New JS, Smith DW, Lobeck WG, Catt JD, Minielli JL, Eison MS, Taylor DP, Riblet LA, Temple DL.
J Med Chem (1986) 29 : 359 -369
PubMed 2869146 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 9.27 9.27

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL422 TRIFLUOPERAZINE 4.0 1 9.27

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL422 TRIFLUOPERAZINE Kd = 0.5322 nM 9.27