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Assay Detail

CHEMBL670523

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
The compound was evaluated for the binding affinity towards Dopamine receptor D2 binding site using [3H]spiroperidol.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

D(2) dopamine receptor (CHEMBL339)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

High affinity and selectivity on 5-HT1A receptor of 1-aryl-4-[1-tetralin)alkyl]piperazines. 2.
Perrone R, Berardi F, Colabufo NA, Leopoldo M, Tortorella V, Fiorentini F, Olgiati V, Ghiglieri A, Govoni S.
J Med Chem (1995) 38 : 942 -949
PubMed 7699710 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.92 5.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL425134 1 5.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL425134 IC50 = 1200.0 nM 5.92