Assay Detail
Binding
CHEMBL671440
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Compound was tested for inhibition of [3H]spiroperidol binding against Dopamine receptor D2
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and dopaminergic binding of 2-aryldopamine analogues: phenethylamines, 3-benzazepines, and 9-(aminomethyl)fluorenes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.00 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53 | APOMORPHINE | 4.0 | 1 | 6.70 |
| CHEMBL611801 | — | — | 1 | 6.59 |
| CHEMBL588 | FENOLDOPAM | 4.0 | 1 | 6.10 |
| CHEMBL60861 | — | — | 1 | 5.75 |
| CHEMBL59 | DOPAMINE | 4.0 | 1 | 5.63 |
| CHEMBL57672 | — | — | 1 | 5.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53 | APOMORPHINE | Ki | = | 200.0 | nM | 6.70 |
| CHEMBL611801 | — | Ki | = | 255.0 | nM | 6.59 |
| CHEMBL588 | FENOLDOPAM | Ki | = | 790.0 | nM | 6.10 |
| CHEMBL60861 | — | Ki | = | 1800.0 | nM | 5.75 |
| CHEMBL59 | DOPAMINE | Ki | = | 2350.0 | nM | 5.63 |
| CHEMBL57672 | — | Ki | = | 5740.0 | nM | 5.24 |