Assay Detail
Binding
CHEMBL672022
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]haloperidol from Dopamine receptor D2 in rat brain
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and potential antipsychotic activity of 1H-imidazo[1,2-c]pyrazolo[3,4-e]pyrimidines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.40 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL479 | THIORIDAZINE | 4.0 | 1 | 8.40 |
| CHEMBL143865 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL479 | THIORIDAZINE | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL143865 | — | IC50 | > | 10000.0 | nM | - |