Assay Detail
Binding
CHEMBL672338
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Binding affinity was tested on Dopamine receptor D2 using radioligand [3H]spiroperidol
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Novel potent sigma 1 ligands: N-[omega-(tetralin-1-yl)alkyl]piperidine derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 9.52 | 9.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1255588 | — | — | 1 | 9.52 |
| CHEMBL135738 | — | — | 1 | - |
| CHEMBL128442 | — | — | 1 | - |
| CHEMBL127006 | — | — | 1 | - |
| CHEMBL134607 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1255588 | — | Ki | = | 0.3 | nM | 9.52 |
| CHEMBL135738 | — | Ki | > | 1850.0 | nM | - |
| CHEMBL128442 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL127006 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL134607 | — | Ki | > | 1850.0 | nM | - |