Assay Detail
Binding
CHEMBL672494
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Binding affinity against the Dopamine receptor D2 in rat striatnrn by using [3H]spiperone radioligand
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
(5S)-3-aryl-5-(1-piperidinylmethyl)-2-oxazolidinones, a new class of potential neuroleptics with a high affinity for sigma receptors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.85 | 5.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL22242 | REMOXIPRIDE | 4.0 | 1 | 5.85 |
| CHEMBL275707 | RIMCAZOLE | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL22242 | REMOXIPRIDE | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL275707 | RIMCAZOLE | IC50 | > | 10000.0 | nM | - |