Assay Detail
Binding
CHEMBL673634
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity against Dopamine receptor D2 of rat striatal mambranes using [3H]spiperone
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
7-Methyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2,3-g]azecine: a new heterocyclic system and a new lead compound for dopamine receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.15 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL441618 | — | — | 1 | 8.22 |
| CHEMBL62529 | — | — | 1 | 7.10 |
| CHEMBL63063 | — | — | 1 | 6.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL441618 | — | Ki | = | 6.0 | nM | 8.22 |
| CHEMBL62529 | — | Ki | = | 79.0 | nM | 7.10 |
| CHEMBL63063 | — | Ki | = | 730.0 | nM | 6.14 |