Assay Detail
Binding
CHEMBL674026
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of EGFR kinase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Pyrimidinylimidazole inhibitors of p38: cyclic N-1 imidazole substituents enhance p38 kinase inhibition and oral activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.08 | 7.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL97162 | — | — | 1 | 7.08 |
| CHEMBL95692 | SB-242235 | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL97162 | — | IC50 | = | 83.0 | nM | 7.08 |
| CHEMBL95692 | SB-242235 | IC50 | > | 10.0 | nM | - |