Assay Detail
Binding
CHEMBL674824
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Compound was evaluated for its ability to displace [3H]raclopride from dopamine receptor D2 in rat striatal homogenates
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Dopaminergic and serotonergic activities of imidazoquinolinones and related compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.82 | 7.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL240773 | QUINPIROLE | 2.0 | 1 | 7.27 |
| CHEMBL1744080 | — | — | 1 | 7.17 |
| CHEMBL12515 | — | — | 1 | 6.03 |
| CHEMBL12247 | — | — | 1 | - |
| CHEMBL2092845 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL240773 | QUINPIROLE | Ki | = | 54.0 | nM | 7.27 |
| CHEMBL1744080 | — | Ki | = | 68.0 | nM | 7.17 |
| CHEMBL12515 | — | Ki | = | 924.0 | nM | 6.03 |
| CHEMBL12247 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL2092845 | — | Ki | > | 1000.0 | nM | - |