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Assay Detail

CHEMBL674974

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Binding
Ancillary Binding affinity towards rat Dopamine receptor D2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

D(2) dopamine receptor (CHEMBL339)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Two novel and potent 3-[(o-methoxyphenyl)piperazinylethyl]-5-phenylthien.
Carroll WA, Sippy KB, Esbenshade TA, Buckner SA, Hancock AA, Meyer MD.
Bioorg Med Chem Lett (2001) 11 : 1119 -1121
PubMed 11354357 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 7.54 7.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL13856 A-123189 1 7.77
CHEMBL268758 A-119637 1 7.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL13856 A-123189 Ki = 17.0 nM 7.77
CHEMBL268758 A-119637 Ki = 50.0 nM 7.30