Assay Detail
Binding
CHEMBL675754
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vivo binding affinity against dopamine (D2) receptor in rat caudate-putamen tissue using [3H]nemonapride as radioligand
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Caudate-putamen |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and affinity of a possible byproduct of electrophilic radiolabeling of [123I]IBZM.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 9.52 | 10.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL54 | HALOPERIDOL | 4.0 | 1 | 10.12 |
| CHEMBL267723 | IOLOPRIDE | 2.0 | 1 | 8.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL54 | HALOPERIDOL | IC50 | = | 0.075 | nM | 10.12 |
| CHEMBL267723 | IOLOPRIDE | IC50 | = | 1.2 | nM | 8.92 |