Assay Detail
Binding
CHEMBL675923
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of binding of [3H]spiroperidol to Dopamine receptor D2 in rat striatal membranes
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Subcellular | Membrane |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Cis- and trans-N-benzyl-octahydrobenzo[g]quinolines. Adrenergic and dopaminergic activity studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.41 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53 | APOMORPHINE | 4.0 | 1 | 6.66 |
| CHEMBL163912 | — | — | 1 | 6.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53 | APOMORPHINE | IC50 | = | 220.0 | nM | 6.66 |
| CHEMBL163912 | — | IC50 | = | 700.0 | nM | 6.16 |