Assay Detail
Functional
CHEMBL680427
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for the agonistic activity of contractile activities of Guinea pig ileum
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Full agonists of CCK8 containing a nonhydrolyzable sulfated tyrosine residue.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 8.46 | 9.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL428666 | — | — | 1 | 9.40 |
| CHEMBL1121 | SINCALIDE | 4.0 | 1 | 9.15 |
| CHEMBL262687 | — | — | 1 | 8.42 |
| CHEMBL217767 | — | — | 1 | 7.77 |
| CHEMBL218455 | — | — | 1 | 7.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL428666 | — | EC50 | = | 0.4 | nM | 9.40 |
| CHEMBL1121 | SINCALIDE | EC50 | = | 0.7 | nM | 9.15 |
| CHEMBL262687 | — | EC50 | = | 3.8 | nM | 8.42 |
| CHEMBL217767 | — | EC50 | = | 17.0 | nM | 7.77 |
| CHEMBL218455 | — | EC50 | = | 28.0 | nM | 7.55 |