Skip to main content
Free research Free research Free target review with research home and workspace preview
Quick search ChEMBL 36
Loading Target Snapshot...
Querying ChEMBL database. This may take a few seconds.
Target Snapshot

CHEMBL369 Target Snapshot

Cavia porcellus · ORGANISM · Cavia porcellus

9,915Compounds
5,947Assays
81Approved Drugs
4,182.0Activities
Free Research Context

Research home keeps recent targets

This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.

Navigation

Switch target

Move to another high-traffic target or paste a specific ChEMBL target ID.

Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Cavia porcellus as ChEMBL target CHEMBL369. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Cavia porcellus
ORGANISM · Cavia porcellus
As of 2026-09-14
ChEMBL target ID
CHEMBL369
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Cavia porcellus still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelCavia porcellus
UniProt AccessionN/A

Cavia porcellus

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Cavia porcellus.

Review nameCavia porcellus
OrganismCavia porcellus
Clinical Profile

Clinical Phase Distribution

81
Approved
5
Phase III
44
Phase II
5
Phase I
Assay Mix

Activity Type Distribution

IC502,217.0
KI49.0
EC501,344.0
KD572.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL415247 10.7 Ki 0.02 Preclinical
CHEMBL88815 10.52 IC50 0.03 Preclinical
CHEMBL573214 10.42 Ki 0.038 Preclinical
CHEMBL287868 10.4 Kd 0.03981 Preclinical
CHEMBL320611 10.39 Kd 0.04074 Preclinical
CHEMBL938 10.32 IC50 0.048 Approved
CHEMBL278789 10.28 IC50 0.052 Preclinical
CHEMBL1169585 10.26 IC50 0.055 Preclinical
CHEMBL90769 10.2 Kd 0.0631 Preclinical
CHEMBL331325 10.15 IC50 0.07 Preclinical
Distribution

pChEMBL Value Distribution

390
5.0
397
5.5
382
6.0
345
6.5
340
7.0
245
7.5
231
8.0
183
8.5
95
9.0
43
9.5
pChEMBL
Approved Drugs

Approved Drugs

CAPSAICIN
CHEMBL294199
Approved 2009
ICATIBANT
CHEMBL2028850
Approved 2008
RIMONABANT
CHEMBL111
Approved 2006
RUPATADINE
CHEMBL91397
Approved 2001
KETOTIFEN
CHEMBL534
Approved 1999
MONTELUKAST
CHEMBL787
Approved 1998
AZELASTINE
CHEMBL639
Approved 1996
REMIFENTANIL
CHEMBL1005
Approved 1996
ZAFIRLUKAST
CHEMBL603
Approved 1996
SERATRODAST
CHEMBL70972
Approved 1995
CETIRIZINE
CHEMBL1000
Approved 1995
LORATADINE
CHEMBL998
Approved 1993
GRANISETRON
CHEMBL289469
Approved 1993
CISAPRIDE
CHEMBL1729
Approved 1993
FELODIPINE
CHEMBL1480
Approved 1991
ONDANSETRON
CHEMBL46
Approved 1991
NIMODIPINE
CHEMBL1428
Approved 1988
ALFENTANIL
CHEMBL634
Approved 1986
TERFENADINE
CHEMBL17157
Approved 1985
GLYBURIDE
CHEMBL472
Approved 1984
MORPHINE
CHEMBL70
Approved 1984
NALTREXONE
CHEMBL19019
Approved 1984
SUFENTANIL
CHEMBL658
Approved 1984
DILTIAZEM HYDROCHLORIDE
CHEMBL1697
Approved 1982
SARALASIN
CHEMBL938
Approved 1982
DILTIAZEM
CHEMBL23
Approved 1982
NIFEDIPINE
CHEMBL193
Approved 1981
BUPRENORPHINE
CHEMBL511142
Approved 1981
ALBUTEROL
CHEMBL714
Approved 1981
VERAPAMIL
CHEMBL6966
Approved 1981
DOBUTAMINE
CHEMBL926
Approved 1978
DISOPYRAMIDE
CHEMBL517
Approved 1977
LOPERAMIDE
CHEMBL841
Approved 1976
SINCALIDE
CHEMBL1121
Approved 1976
DIGOXIN
CHEMBL1751
Approved 1975
PYRILAMINE
CHEMBL511
Approved 1973
PYRILAMINE MALEATE
CHEMBL1201006
Approved 1973
CARBACHOL
CHEMBL14
Approved 1972
FENTANYL
CHEMBL596
Approved 1968
PROPRANOLOL
CHEMBL27
Approved 1967
EPINEPHRINE
CHEMBL679
Approved 1965
ATROPINE
CHEMBL517712
Approved 1960
ATROPINE SULFATE
CHEMBL2146146
Approved 1960
OXYMORPHONE
CHEMBL963
Approved 1959
ISOPROTERENOL
CHEMBL434
Approved 1956
QUINIDINE
CHEMBL1294
Approved 1950
HISTAMINE
CHEMBL90
Approved 1939
Assay Landscape

Assay Landscape

5,947
Total Assays
2,407
Tested Compounds
3
Assay Types
Functional — 5,354 assays, 2,407 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 5,347 2,407 6.5
assay format 7 0
Toxicity — 309 assays, 11 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 304 11 4.0
assay format 5 0
ADME — 284 assays, 9 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 282 9 7.1
assay format 2 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine