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Assay Detail

CHEMBL680569

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Affinity on glycogen phosphorylase (GP) enzyme.
30
Total Activities
27
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Three-dimensional quantitative structure-activity relationships from molecular similarity matrices and genetic neural networks. 2. Applications.
So SS, Karplus M.
J Med Chem (1997) 40 : 4360 -4371
PubMed 9435905 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 30 4.57 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3351144 1 5.52
CHEMBL133097 1 4.80
CHEMBL3351143 1 4.50
CHEMBL3351132 1 4.35
CHEMBL3351152 1 4.23
CHEMBL3351139 1 4.03
CHEMBL136618 1 -
CHEMBL3351136 1 -
CHEMBL3351153 1 -
CHEMBL3351145 1 -
CHEMBL3351141 1 -
CHEMBL284555 1 -
CHEMBL71477 1 -
CHEMBL334655 2 -
CHEMBL3351150 1 -
CHEMBL335028 1 -
CHEMBL134001 1 -
CHEMBL35946 2 -
CHEMBL1222250 DEXTROSE 4.0 1 -
CHEMBL3351149 1 -
CHEMBL35563 1 -
CHEMBL3351138 1 -
CHEMBL35757 2 -
CHEMBL3351135 1 -
CHEMBL3215399 1 -
CHEMBL423484 1 -
CHEMBL3351133 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3351144 Ki = 2999.16 nM 5.52
CHEMBL133097 Ki = 15995.58 nM 4.80
CHEMBL3351143 Ki = 31988.95 nM 4.50
CHEMBL3351132 Ki = 44977.99 nM 4.35
CHEMBL3351152 Ki = 59020.11 nM 4.23
CHEMBL3351139 Ki = 93972.33 nM 4.03
CHEMBL35946 Ki = 36728230.05 nM -
CHEMBL136618 Ki = 18879913.49 nM -
CHEMBL134001 Ki = 1999861.87 nM -
CHEMBL3351133 Ki = 21086281.5 nM -
CHEMBL3351150 Ki = 369828.18 nM -
CHEMBL334655 Ki = 399944.75 nM -
CHEMBL71477 Ki = 16788040.18 nM -
CHEMBL284555 Ki = 2798981.32 nM -
CHEMBL3351141 Ki = 990831.94 nM -
CHEMBL3351145 Ki = 1300169.58 nM -
CHEMBL3351153 Ki = 145881.43 nM -
CHEMBL3351136 Ki = 1798870.92 nM -
CHEMBL423484 Ki = 4797334.49 nM -
CHEMBL3215399 Ki = 16292960.33 nM -
CHEMBL35946 Ki = 159955.8 nM -
CHEMBL35757 Ki = 369828.18 nM -
CHEMBL334655 Ki = 2999162.52 nM -
CHEMBL3351135 Ki = 3597493.35 nM -
CHEMBL335028 Ki = 15205475.3 nM -
CHEMBL3351138 Ki = 139958.73 nM -
CHEMBL35563 Ki = 5597576.01 nM -
CHEMBL3351149 Ki = 16904409.32 nM -
CHEMBL1222250 DEXTROSE Ki = 1698243.65 nM -
CHEMBL35757 Ki = 439541.62 nM -