Assay Detail
Binding
CHEMBL683428
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Concentration required to inhibit fatty acid amide hydrolase (FAAH) at pH 7.0
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
An endogenous sleep-inducing compound is a novel competitive inhibitor of fatty acid amide hydrolase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.51 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL345382 | — | — | 1 | 6.16 |
| CHEMBL414450 | — | — | 1 | 5.60 |
| CHEMBL157736 | — | — | 1 | 5.28 |
| CHEMBL422064 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL345382 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL414450 | — | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL157736 | — | IC50 | = | 5300.0 | nM | 5.28 |
| CHEMBL422064 | — | IC50 | = | 9900.0 | nM | 5.00 |