Assay Detail
Functional
CHEMBL684296
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested in vitro for its inhibitory activity against human epidermoid carcinoma cell (H. Ep. 2) growth at a concentration of 10 uM
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and biological activity of certain alkyl 5-(alkoxycarbonyl)-1H-benzimidazole-2-carbamates and related derivatives: a new class of potential antineoplastic and antifilarial agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 6.26 | 7.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL9514 | NOCODAZOLE | 2.0 | 1 | 7.48 |
| CHEMBL149748 | — | — | 1 | 6.66 |
| CHEMBL433544 | — | — | 1 | 6.62 |
| CHEMBL151945 | — | — | 1 | 6.54 |
| CHEMBL155162 | — | — | 1 | 6.41 |
| CHEMBL346848 | — | — | 1 | 5.96 |
| CHEMBL155223 | — | — | 1 | 5.80 |
| CHEMBL150923 | — | — | 1 | 5.64 |
| CHEMBL150659 | — | — | 1 | 5.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL9514 | NOCODAZOLE | IC50 | = | 33.0 | nM | 7.48 |
| CHEMBL149748 | — | IC50 | = | 220.0 | nM | 6.66 |
| CHEMBL433544 | — | IC50 | = | 240.0 | nM | 6.62 |
| CHEMBL151945 | — | IC50 | = | 290.0 | nM | 6.54 |
| CHEMBL155162 | — | IC50 | = | 390.0 | nM | 6.41 |
| CHEMBL346848 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL155223 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL150923 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL150659 | — | IC50 | = | 6000.0 | nM | 5.22 |