Compound Detail
CHEMBL155162
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Basic Information
| ChEMBL ID | CHEMBL155162 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PIYYGWXITCXKHV-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
305.3
MW (Da)
3.09
ALogP
5
HBA
2
HBD
93.3
PSA (Ų)
0.85
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.41
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Homo sapiens CHEMBL372 | IC50 | 6.41 | 6.41 | 390.0 | 1 |
| L1210 CHEMBL386 | IC50 | 6.14 | 6.14 | 730.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Homo sapiens | IC50 | = | 390.0 | nM | 6.41 | Compound was tested in vitro for its inhibitory activity against human epidermoi... | 1738146 |
| L1210 | IC50 | = | 730.0 | nM | 6.14 | In vitro for its inhibitory activity against L1210 murine leukemia cell growth | 1738146 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1738146 | 10.1021/jm00081a016 | L1210 | 2 |
| 1738146 | 10.1021/jm00081a016 | Homo sapiens | 2 |
| 1738146 | 10.1021/jm00081a016 | Brugia pahangi | 1 |
Data from ChEMBL 36 via Core Engine