Assay Detail
Functional
CHEMBL684498
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity was assessed as the concentration which gave a 50% increase in the response to electrical stimulation in the guinea pig ileum and is expressed as percent of the maximum 5-HT response = 78%
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Arylcarbamate derivatives of 1-piperidineethanol as potent ligands for 5-HT4 receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 8.40 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL286136 | — | — | 1 | 8.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL286136 | — | EC50 | = | 4.0 | nM | 8.40 |