Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL684553

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Effective concentration required for its inhibition of nonspecific binding to guinea pig ileal membranes
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cavia porcellus
Confidence 1 — Organism
Curated By Intermediate

Target

Cavia porcellus (CHEMBL369)
Type ORGANISM
Organism Cavia porcellus

Publication

Design and synthesis of side-chain conformationally restricted phenylalanines and their use for structure-activity studies on tachykinin NK-1 receptor.
Josien H, Lavielle S, Brunissen A, Saffroy M, Torrens Y, Beaujouan JC, Glowinski J, Chassaing G.
J Med Chem (1994) 37 : 1586 -1601
PubMed 7515443 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.47 8.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2372521 1 8.47

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2372521 EC50 = 3.4 nM 8.47