Assay Detail
Functional
CHEMBL684975
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50% inhibitory concentration on the LTD4 (100 nM) induced contraction of guinea-pig tracheal strip bioassay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Trachea |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel phthalimide derivatives, designed as leukotriene D(4) receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.75 | 8.99 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL603 | ZAFIRLUKAST | 4.0 | 1 | 8.99 |
| CHEMBL38670 | — | — | 1 | 4.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL603 | ZAFIRLUKAST | IC50 | = | 1.03 | nM | 8.99 |
| CHEMBL38670 | — | IC50 | = | 31200.0 | nM | 4.51 |