Assay Detail
Functional
CHEMBL685019
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Inhibitory effect on electrically induced contraction of guinea pig ileum (GPI)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
A photoaffinity reagent to label the opiate receptors of guinea pig ileum and mouse vas deferens.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.85 | 8.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2371596 | — | — | 1 | 8.36 |
| CHEMBL2311114 | — | — | 1 | 8.28 |
| CHEMBL35838 | [LEU5]ENKEPHALIN | — | 1 | 6.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2371596 | — | IC50 | = | 4.35 | nM | 8.36 |
| CHEMBL2311114 | — | IC50 | = | 5.23 | nM | 8.28 |
| CHEMBL35838 | [LEU5]ENKEPHALIN | IC50 | = | 120.0 | nM | 6.92 |