Assay Detail
Functional
CHEMBL685157
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In vivo inhibitory activity against platelet aggregation in guinea pigs
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and bioactivities of heterocyclic lipids as PAF antagonists. 2
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.39 | 7.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL12183 | — | — | 1 | 7.68 |
| CHEMBL12558 | — | — | 1 | 7.54 |
| CHEMBL274420 | CV-6209 | — | 1 | 7.26 |
| CHEMBL12438 | — | — | 1 | 7.25 |
| CHEMBL12554 | — | — | 1 | 7.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL12183 | — | IC50 | = | 21.0 | nM | 7.68 |
| CHEMBL12558 | — | IC50 | = | 29.0 | nM | 7.54 |
| CHEMBL274420 | CV-6209 | IC50 | = | 55.0 | nM | 7.26 |
| CHEMBL12438 | — | IC50 | = | 56.0 | nM | 7.25 |
| CHEMBL12554 | — | IC50 | = | 57.0 | nM | 7.24 |