Assay Detail
Functional
CHEMBL685495
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In vitro contractile response of histamine at 0.5 ug/mL in guinea pig ileum
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Cardiotonic agents. 6. Histamine analogues as potential cardiovascular selective H2 agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.80 | 6.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL90 | HISTAMINE | 4.0 | 1 | 6.62 |
| CHEMBL12344 | DIMAPRIT | — | 1 | 4.98 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL90 | HISTAMINE | EC50 | = | 240.0 | nM | 6.62 |
| CHEMBL12344 | DIMAPRIT | EC50 | = | 10400.0 | nM | 4.98 |