Assay Detail
Functional
CHEMBL685498
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Calcium channel agonist activity in guinea pig ileum longitudinal smooth muscle (GPILSM) at 10e-5 M
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Syntheses, calcium channel agonist-antagonist modulation activities, and voltage-clamp studies of isopropyl 1,4-dihydro-2,6-dimethyl-3-nitro-4-pyridinylpyridine-5-carboxylate racemates and enantiomers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 4.39 | 4.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL97381 | — | — | 1 | 4.46 |
| CHEMBL97047 | — | — | 1 | 4.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL97381 | — | EC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL97047 | — | EC50 | = | 48000.0 | nM | 4.32 |