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Assay Detail

CHEMBL686216

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Functional
Antagonistic activity expressed as pA2 in Guinea pig lung strip assay.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cavia porcellus
Tissue Lung
Confidence 1 — Organism
Curated By Intermediate

Target

Cavia porcellus (CHEMBL369)
Type ORGANISM
Organism Cavia porcellus

Publication

Highly selective bradykinin agonists and antagonists with replacement of proline residues by N-methyl-D- and L-phenylalanine.
Reissmann S, Schwuchow C, Seyfarth L, Pineda De Castro LF, Liebmann C, Paegelow I, Werner H, Stewart JM.
J Med Chem (1996) 39 : 929 -936
PubMed 8632416 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 5.59 5.59

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL411444 1 5.59

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL411444 Kd = 2570.4 nM 5.59