Assay Detail
Functional
CHEMBL686994
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Dissociation constant of the drug-receptor complex was measured in guinea pig urinary bladder
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Dimethylsulfonium and thiolanium analogues of the muscarinic agent oxotremorine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 5 | 5.47 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL553214 | — | — | 1 | 5.96 |
| CHEMBL540395 | — | — | 1 | 5.89 |
| CHEMBL23957 | OXOTREMORINE METHIODIDE | — | 1 | 5.37 |
| CHEMBL541927 | — | — | 1 | 5.23 |
| CHEMBL554629 | — | — | 1 | 4.88 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL553214 | — | Kd | = | 1100.0 | nM | 5.96 |
| CHEMBL540395 | — | Kd | = | 1300.0 | nM | 5.89 |
| CHEMBL23957 | OXOTREMORINE METHIODIDE | Kd | = | 4300.0 | nM | 5.37 |
| CHEMBL541927 | — | Kd | = | 5900.0 | nM | 5.23 |
| CHEMBL554629 | — | Kd | = | 13100.0 | nM | 4.88 |