Assay Detail
Functional
CHEMBL687341
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro effect of compound on leukotriene-D4 LTD4 (100 nM) induced contraction of isolated guinea pig tracheal strip
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Trachea |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis and pharmacological evaluation of novel pyrazolo[3,4-b]thieno[2,3-d]pyridine acid derivatives: a new class of anti-inflammatory and anti-platelet agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.99 | 8.99 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL603 | ZAFIRLUKAST | 4.0 | 1 | 8.99 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL603 | ZAFIRLUKAST | IC50 | = | 1.03 | nM | 8.99 |