Assay Detail
Functional
CHEMBL687745
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Calcium channel agonist activity in guinea pig left atrium (GPLA) at 10e-6 M
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Cardiac atrium |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Syntheses, calcium channel agonist-antagonist modulation activities, and voltage-clamp studies of isopropyl 1,4-dihydro-2,6-dimethyl-3-nitro-4-pyridinylpyridine-5-carboxylate racemates and enantiomers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.05 | 5.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL97381 | — | — | 1 | 5.09 |
| CHEMBL53390 | — | — | 1 | 5.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL97381 | — | EC50 | = | 8050.0 | nM | 5.09 |
| CHEMBL53390 | — | EC50 | = | 9670.0 | nM | 5.01 |