Assay Detail
Functional
CHEMBL687944
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Opioid agonist potencies was determined by electrically stimulated guinea pig ileum (GPI)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Hybrid bivalent ligands with opiate and enkephalin pharmacophores.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.50 | 8.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL607320 | — | — | 1 | 8.12 |
| CHEMBL607319 | — | — | 1 | 6.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL607320 | — | IC50 | = | 7.5 | nM | 8.12 |
| CHEMBL607319 | — | IC50 | = | 136.0 | nM | 6.87 |