Assay Detail
Functional
CHEMBL688009
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In vitro concentration required to induce contraction of isolated GPGB
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Modification of receptor selectivity and functional activity in cholecystokinin peptoid ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 7.96 | 9.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1121 | SINCALIDE | 4.0 | 1 | 9.41 |
| CHEMBL319438 | — | — | 1 | 8.80 |
| CHEMBL432256 | — | — | 1 | 7.56 |
| CHEMBL432258 | — | — | 1 | 6.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1121 | SINCALIDE | EC50 | = | 0.389 | nM | 9.41 |
| CHEMBL319438 | — | EC50 | = | 1.585 | nM | 8.80 |
| CHEMBL432256 | — | EC50 | = | 27.54 | nM | 7.56 |
| CHEMBL432258 | — | EC50 | = | 831.76 | nM | 6.08 |