Assay Detail
Functional
CHEMBL688551
Review assay metadata, readout intent, target linkage, and publication context from the same page.
pA2 value against guinea pig ileum.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
NMR and computational evidence that high-affinity bradykinin receptor antagonists adopt C-terminal beta-turns.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 8.50 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2028850 | ICATIBANT | 4.0 | 1 | 8.70 |
| CHEMBL2369941 | — | — | 1 | 8.50 |
| CHEMBL2028979 | — | — | 1 | 8.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2028850 | ICATIBANT | Kd | = | 1.995 | nM | 8.70 |
| CHEMBL2369941 | — | Kd | = | 3.162 | nM | 8.50 |
| CHEMBL2028979 | — | Kd | = | 5.012 | nM | 8.30 |