Assay Detail
Functional
CHEMBL688858
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Antioxidative activity was evaluated by using the lipid peroxidation of guinea pig liver microsomes
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Liver |
| Subcellular | Microsomes |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Total synthesis of an antioxidant isolated from yeast via palladium-catalyzed coupling and its application for related compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.20 | 4.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL8115 | — | — | 1 | 4.36 |
| CHEMBL7983 | PROPYL GALLATE | 1.0 | 1 | 4.30 |
| CHEMBL7998 | — | — | 1 | 4.25 |
| CHEMBL274614 | — | — | 1 | 4.19 |
| CHEMBL8174 | — | — | 1 | 4.08 |
| CHEMBL274615 | — | — | 1 | 4.01 |
| CHEMBL47 | ALPHA-TOCOPHEROL | — | 1 | - |
| CHEMBL267296 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL8115 | — | IC50 | = | 44000.0 | nM | 4.36 |
| CHEMBL7983 | PROPYL GALLATE | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL7998 | — | IC50 | = | 56000.0 | nM | 4.25 |
| CHEMBL274614 | — | IC50 | = | 65000.0 | nM | 4.19 |
| CHEMBL8174 | — | IC50 | = | 83000.0 | nM | 4.08 |
| CHEMBL274615 | — | IC50 | = | 98000.0 | nM | 4.01 |
| CHEMBL47 | ALPHA-TOCOPHEROL | IC50 | = | 280000.0 | nM | - |
| CHEMBL267296 | — | IC50 | = | 107000.0 | nM | - |