Assay Detail
Functional
CHEMBL689053
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested in vitro for inhibiting electrically stimulated muscle contractions in guinea pig ileum (GPI)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Solid phase synthesis of C-terminal carbohydrate modified enkephalins
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.26 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2369514 | — | — | 1 | 6.96 |
| CHEMBL2369528 | — | — | 1 | 6.70 |
| CHEMBL35838 | [LEU5]ENKEPHALIN | — | 1 | 6.27 |
| CHEMBL307868 | — | — | 1 | 5.98 |
| CHEMBL2369513 | — | — | 1 | 5.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2369514 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL2369528 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL35838 | [LEU5]ENKEPHALIN | IC50 | = | 540.0 | nM | 6.27 |
| CHEMBL307868 | — | IC50 | = | 1040.0 | nM | 5.98 |
| CHEMBL2369513 | — | IC50 | = | 3860.0 | nM | 5.41 |