Assay Detail
Functional
CHEMBL689278
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was evaluated for inhibition of specific binding of [3H]U-46619 to guinea pig platelet membrane.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and thromboxane A2/prostaglandin H2 receptor antagonistic activity of phenol derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.78 | 8.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL420002 | — | — | 1 | 8.36 |
| CHEMBL70411 | — | — | 1 | 7.89 |
| CHEMBL67653 | — | — | 1 | 7.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL420002 | — | IC50 | = | 4.4 | nM | 8.36 |
| CHEMBL70411 | — | IC50 | = | 13.0 | nM | 7.89 |
| CHEMBL67653 | — | IC50 | = | 80.0 | nM | 7.10 |