Assay Detail
Functional
CHEMBL690228
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration of compound for the agonistic activity on guinea pig ileum
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Heterocyclic muscarinic agonists. Synthesis and biological activity of some bicyclic sulfonium arecoline bioisosteres.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.09 | 5.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL25649 | — | — | 1 | 5.09 |
| CHEMBL283834 | — | — | 1 | - |
| CHEMBL418022 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL25649 | — | EC50 | = | 8200.0 | nM | 5.09 |
| CHEMBL283834 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL418022 | — | EC50 | > | 50000.0 | nM | - |